Ovarian mature cystic teratoma with malignant transformation: two case reports

BACKGROUND: Mature Cystic Teratoma (MCT) is a benign tumor that can lead to malignant transformation (MT) in 1–3% of cases. Management of MT is a big challenge for gynecologic oncologists due to the lack of specific diagnostic and treatment protocols. CASE PRESENTATION: We reported two Iranian cases...

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Autores principales: Tehranian, Afsaneh, Ghahghaei-Nezamabadi, Akram, Seifollahi, Akram, Kasraei, Sara, Dehghani-Nejad, Hamideh, Maleki-Hajiagha, Arezoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7839193/
https://www.ncbi.nlm.nih.gov/pubmed/33499917
http://dx.doi.org/10.1186/s13256-020-02594-4
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author Tehranian, Afsaneh
Ghahghaei-Nezamabadi, Akram
Seifollahi, Akram
Kasraei, Sara
Dehghani-Nejad, Hamideh
Maleki-Hajiagha, Arezoo
author_facet Tehranian, Afsaneh
Ghahghaei-Nezamabadi, Akram
Seifollahi, Akram
Kasraei, Sara
Dehghani-Nejad, Hamideh
Maleki-Hajiagha, Arezoo
author_sort Tehranian, Afsaneh
collection PubMed
description BACKGROUND: Mature Cystic Teratoma (MCT) is a benign tumor that can lead to malignant transformation (MT) in 1–3% of cases. Management of MT is a big challenge for gynecologic oncologists due to the lack of specific diagnostic and treatment protocols. CASE PRESENTATION: We reported two Iranian cases of MT of MCT with two different stages and prognosis. Our both cases presented the same symptoms, including chronic abdominal pain and distention, loss of appetite, and weight loss. In case number 1, despite the large size of the tumor, the disease was at stage Ia and had a good prognosis; while, case number 2 was at stage IIIc of the disease with a poor prognosis. CONCLUSION: The stage of the disease is the most important prognostic factor, and early diagnosis and treatment are very critical for better survival.
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spelling pubmed-78391932021-01-27 Ovarian mature cystic teratoma with malignant transformation: two case reports Tehranian, Afsaneh Ghahghaei-Nezamabadi, Akram Seifollahi, Akram Kasraei, Sara Dehghani-Nejad, Hamideh Maleki-Hajiagha, Arezoo J Med Case Rep Case Report BACKGROUND: Mature Cystic Teratoma (MCT) is a benign tumor that can lead to malignant transformation (MT) in 1–3% of cases. Management of MT is a big challenge for gynecologic oncologists due to the lack of specific diagnostic and treatment protocols. CASE PRESENTATION: We reported two Iranian cases of MT of MCT with two different stages and prognosis. Our both cases presented the same symptoms, including chronic abdominal pain and distention, loss of appetite, and weight loss. In case number 1, despite the large size of the tumor, the disease was at stage Ia and had a good prognosis; while, case number 2 was at stage IIIc of the disease with a poor prognosis. CONCLUSION: The stage of the disease is the most important prognostic factor, and early diagnosis and treatment are very critical for better survival. BioMed Central 2021-01-27 /pmc/articles/PMC7839193/ /pubmed/33499917 http://dx.doi.org/10.1186/s13256-020-02594-4 Text en © The Author(s) 2021 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Tehranian, Afsaneh
Ghahghaei-Nezamabadi, Akram
Seifollahi, Akram
Kasraei, Sara
Dehghani-Nejad, Hamideh
Maleki-Hajiagha, Arezoo
Ovarian mature cystic teratoma with malignant transformation: two case reports
title Ovarian mature cystic teratoma with malignant transformation: two case reports
title_full Ovarian mature cystic teratoma with malignant transformation: two case reports
title_fullStr Ovarian mature cystic teratoma with malignant transformation: two case reports
title_full_unstemmed Ovarian mature cystic teratoma with malignant transformation: two case reports
title_short Ovarian mature cystic teratoma with malignant transformation: two case reports
title_sort ovarian mature cystic teratoma with malignant transformation: two case reports
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7839193/
https://www.ncbi.nlm.nih.gov/pubmed/33499917
http://dx.doi.org/10.1186/s13256-020-02594-4
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AT kasraeisara ovarianmaturecysticteratomawithmalignanttransformationtwocasereports
AT dehghaninejadhamideh ovarianmaturecysticteratomawithmalignanttransformationtwocasereports
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