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Age itself or age-associated comorbidities? A nationwide analysis of outcomes of geriatric trauma

PURPOSE: Geriatric trauma patients present physiological challenges to care providers. A nationwide analysis was performed to evaluate the roles of age alone versus age-associated comorbidities in the morbidity and mortality of elderly patients with blunt abdominal trauma (BAT). METHODS: Patients wi...

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Autores principales: Fu, Chih-Yuan, Bajani, Francesco, Bokhari, Marissa, Starr, Frederick, Messer, Thomas, Kaminsky, Matthew, Dennis, Andrew, Schlanser, Victoria, Mis, Justin, Poulakidas, Stathis, Bokhari, Faran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7839290/
https://www.ncbi.nlm.nih.gov/pubmed/33502566
http://dx.doi.org/10.1007/s00068-020-01595-8
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author Fu, Chih-Yuan
Bajani, Francesco
Bokhari, Marissa
Starr, Frederick
Messer, Thomas
Kaminsky, Matthew
Dennis, Andrew
Schlanser, Victoria
Mis, Justin
Poulakidas, Stathis
Bokhari, Faran
author_facet Fu, Chih-Yuan
Bajani, Francesco
Bokhari, Marissa
Starr, Frederick
Messer, Thomas
Kaminsky, Matthew
Dennis, Andrew
Schlanser, Victoria
Mis, Justin
Poulakidas, Stathis
Bokhari, Faran
author_sort Fu, Chih-Yuan
collection PubMed
description PURPOSE: Geriatric trauma patients present physiological challenges to care providers. A nationwide analysis was performed to evaluate the roles of age alone versus age-associated comorbidities in the morbidity and mortality of elderly patients with blunt abdominal trauma (BAT). METHODS: Patients with BAT registered in the National Trauma Data Bank from 2013 to 2015 were analyzed using propensity score matching (PSM) to evaluate the mortality rate, complication rate, hospital length of stay (LOS), intensive care unit (ICU) LOS and ventilator days between young (age < 65) and elderly (age ≥ 65) patients. An adjusted multivariate logistic regression (MLR) model was also used to evaluate the effect of age itself and age-associated comorbidities on mortality. RESULTS: There were 41,880 patients with BAT during the study period. In elderly patients, the injury severity score (ISS) decreased with age, but the mortality rate increased inversely (from 5.0 to 13.5%). Under a similar condition and proportion of age-associated comorbidities after a well-batched PSM analysis, elderly patients had significantly higher mortality rates (8.0% vs. 1.9%, p < 0.001), higher complication rates (35.1% vs. 30.6%, p < 0.001), longer hospital LOS (8.9 vs. 8.1 days, p < 0.001), longer ICU LOS (3.7 vs. 2.7 days, p < 0.001) and more ventilator days (1.1 vs. 0.5 days, p < 0.001) than young patients. Furthermore, the MLR analysis showed that age itself served as an independent factor for mortality (odds ratio: 1.049, 95% CI 1.043–1.055, p < 0.001), but age-associated comorbidity was not. CONCLUSION: In patients with BAT, age itself appeared to have an independent and deleterious effect on mortality, but age-associated comorbidity did not. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00068-020-01595-8.
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spelling pubmed-78392902021-01-28 Age itself or age-associated comorbidities? A nationwide analysis of outcomes of geriatric trauma Fu, Chih-Yuan Bajani, Francesco Bokhari, Marissa Starr, Frederick Messer, Thomas Kaminsky, Matthew Dennis, Andrew Schlanser, Victoria Mis, Justin Poulakidas, Stathis Bokhari, Faran Eur J Trauma Emerg Surg Original Article PURPOSE: Geriatric trauma patients present physiological challenges to care providers. A nationwide analysis was performed to evaluate the roles of age alone versus age-associated comorbidities in the morbidity and mortality of elderly patients with blunt abdominal trauma (BAT). METHODS: Patients with BAT registered in the National Trauma Data Bank from 2013 to 2015 were analyzed using propensity score matching (PSM) to evaluate the mortality rate, complication rate, hospital length of stay (LOS), intensive care unit (ICU) LOS and ventilator days between young (age < 65) and elderly (age ≥ 65) patients. An adjusted multivariate logistic regression (MLR) model was also used to evaluate the effect of age itself and age-associated comorbidities on mortality. RESULTS: There were 41,880 patients with BAT during the study period. In elderly patients, the injury severity score (ISS) decreased with age, but the mortality rate increased inversely (from 5.0 to 13.5%). Under a similar condition and proportion of age-associated comorbidities after a well-batched PSM analysis, elderly patients had significantly higher mortality rates (8.0% vs. 1.9%, p < 0.001), higher complication rates (35.1% vs. 30.6%, p < 0.001), longer hospital LOS (8.9 vs. 8.1 days, p < 0.001), longer ICU LOS (3.7 vs. 2.7 days, p < 0.001) and more ventilator days (1.1 vs. 0.5 days, p < 0.001) than young patients. Furthermore, the MLR analysis showed that age itself served as an independent factor for mortality (odds ratio: 1.049, 95% CI 1.043–1.055, p < 0.001), but age-associated comorbidity was not. CONCLUSION: In patients with BAT, age itself appeared to have an independent and deleterious effect on mortality, but age-associated comorbidity did not. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00068-020-01595-8. Springer Berlin Heidelberg 2021-01-27 2022 /pmc/articles/PMC7839290/ /pubmed/33502566 http://dx.doi.org/10.1007/s00068-020-01595-8 Text en © Springer-Verlag GmbH, DE part of Springer Nature 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Original Article
Fu, Chih-Yuan
Bajani, Francesco
Bokhari, Marissa
Starr, Frederick
Messer, Thomas
Kaminsky, Matthew
Dennis, Andrew
Schlanser, Victoria
Mis, Justin
Poulakidas, Stathis
Bokhari, Faran
Age itself or age-associated comorbidities? A nationwide analysis of outcomes of geriatric trauma
title Age itself or age-associated comorbidities? A nationwide analysis of outcomes of geriatric trauma
title_full Age itself or age-associated comorbidities? A nationwide analysis of outcomes of geriatric trauma
title_fullStr Age itself or age-associated comorbidities? A nationwide analysis of outcomes of geriatric trauma
title_full_unstemmed Age itself or age-associated comorbidities? A nationwide analysis of outcomes of geriatric trauma
title_short Age itself or age-associated comorbidities? A nationwide analysis of outcomes of geriatric trauma
title_sort age itself or age-associated comorbidities? a nationwide analysis of outcomes of geriatric trauma
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7839290/
https://www.ncbi.nlm.nih.gov/pubmed/33502566
http://dx.doi.org/10.1007/s00068-020-01595-8
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