CDKN1B mutation and copy number variation are associated with tumor aggressiveness in luminal breast cancer

The CDKN1B gene, encoding for the CDK inhibitor p27(kip1), is mutated in defined human cancer subtypes, including breast, prostate carcinomas and small intestine neuroendocrine tumors. Lessons learned from small intestine neuroendocrine tumors suggest that CDKN1B mutations could be subclonal, raisin...

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Detalles Bibliográficos
Autores principales: Viotto, Davide, Russo, Francesca, Anania, Ilaria, Segatto, Ilenia, Rampioni Vinciguerra, Gian Luca, Dall'Acqua, Alessandra, Bomben, Riccardo, Perin, Tiziana, Cusan, Martina, Schiappacassi, Monica, Gerratana, Lorenzo, D'Andrea, Sara, Citron, Francesca, Vit, Filippo, Musco, Lorena, Mattevi, Maria Chiara, Mungo, Giorgia, Nicoloso, Milena S, Sonego, Maura, Massarut, Samuele, Sorio, Roberto, Barzan, Luigi, Franchin, Giovanni, Giorda, Giorgio, Lucia, Emilio, Sulfaro, Sandro, Giacomarra, Vittorio, Polesel, Jerry, Toffolutti, Federica, Canzonieri, Vincenzo, Puglisi, Fabio, Gattei, Valter, Vecchione, Andrea, Belletti, Barbara, Baldassarre, Gustavo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2020
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7839435/
https://www.ncbi.nlm.nih.gov/pubmed/33140857
http://dx.doi.org/10.1002/path.5584

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