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5-((1H-imidazol-1-yl)methyl)quinolin-8-ol as potential antiviral SARS-CoV-2 candidate: Synthesis, crystal structure, Hirshfeld surface analysis, DFT and molecular docking studies

A potential new drug to treat SARS-CoV-2 infections and chloroquine analogue, 5-((1H-imidazol-1-yl)methyl)quinolin-8-ol (DD1) has been here synthesized and characterized by FT-IR, (1)H-NMR, (13)C-NMR, ultraviolet-visible, ESI-MS and single-crystal X-ray diffraction. DD1 was optimized in gas phase, a...

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Detalles Bibliográficos
Autores principales:	Douche, Dhaybia, Sert, Yusuf, Brandán, Silvia A., Kawther, Ameed Ahmed, Bilmez, Bayram, Dege, Necmi, Louzi, Ahmed El, Bougrin, Khalid, Karrouchi, Khalid, Himmi, Banacer
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier B.V. 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7839438/ https://www.ncbi.nlm.nih.gov/pubmed/33526951 http://dx.doi.org/10.1016/j.molstruc.2021.130005

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