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Regioselective Bromine/Magnesium Exchange for the Selective Functionalization of Polyhalogenated Arenes and Heterocycles
Using the bimetallic combination sBu(2)Mg⋅2 LiOR (R=2‐ethylhexyl) in toluene enables efficient and regioselective Br/Mg exchanges with various dibromo‐arenes and ‐heteroarenes under mild reaction conditions and provides bromo‐substituted magnesium reagents. Assessing the role of Lewis donor additive...
Autores principales: | Desaintjean, Alexandre, Haupt, Tobias, Bole, Leonie J., Judge, Neil R., Hevia, Eva, Knochel, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7839478/ https://www.ncbi.nlm.nih.gov/pubmed/33079466 http://dx.doi.org/10.1002/anie.202012496 |
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