Liquid Biopsy Enables Quantification of the Abundance and Interindividual Variability of Hepatic Enzymes and Transporters

Variability in individual capacity for hepatic elimination of therapeutic drugs is well recognized and is associated with variable expression and activity of liver enzymes and transporters. Although genotyping offers some degree of stratification, there is often large variability within the same gen...

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Detalles Bibliográficos
Autores principales: Achour, Brahim, Al‐Majdoub, Zubida M., Grybos‐Gajniak, Agnieszka, Lea, Kristi, Kilford, Peter, Zhang, Mian, Knight, David, Barber, Jill, Schageman, Jeoffrey, Rostami‐Hodjegan, Amin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7839483/
https://www.ncbi.nlm.nih.gov/pubmed/33141922
http://dx.doi.org/10.1002/cpt.2102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7839483/
https://www.ncbi.nlm.nih.gov/pubmed/33141922
http://dx.doi.org/10.1002/cpt.2102

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