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Hepatitis B virus RNA decline without concomitant viral antigen decrease is associated with a low probability of sustained response and hepatitis B surface antigen loss

BACKGROUND: Serum hepatitis B virus (HBV) RNA may reflect intrahepatic HBV replication. Novel anti‐viral drugs have shown potent HBV RNA decline without concomitant hepatitis B surface antigen (HBsAg) decrease. How this relates to off‐treatment response is yet unclear. AIM: To study the degree of on...

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Detalles Bibliográficos
Autores principales: Brakenhoff, Sylvia M., de Man, Robert A., Boonstra, André, van Campenhout, Margo J. H., de Knegt, Robert J., van Bömmel, Florian, van der Eijk, Annemiek A., Berg, Thomas, Hansen, Bettina E., Janssen, Harry L. A., Sonneveld, Milan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7839551/
https://www.ncbi.nlm.nih.gov/pubmed/33222190
http://dx.doi.org/10.1111/apt.16172