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Adaptive enrichment trials: What are the benefits?

When planning a Phase III clinical trial, suppose a certain subset of patients is expected to respond particularly well to the new treatment. Adaptive enrichment designs make use of interim data in selecting the target population for the remainder of the trial, either continuing with the full popula...

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Detalles Bibliográficos
Autores principales: Burnett, Thomas, Jennison, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7839594/
https://www.ncbi.nlm.nih.gov/pubmed/33244786
http://dx.doi.org/10.1002/sim.8797

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