A Photoclick‐Based High‐Throughput Screening for the Directed Evolution of Decarboxylase OleT

Enzymatic oxidative decarboxylation is an up‐and‐coming reaction yet lacking efficient screening methods for the directed evolution of decarboxylases. Here, we describe a simple photoclick assay for the detection of decarboxylation products and its application in a proof‐of‐principle directed evolut...

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Detalles Bibliográficos
Autores principales: Markel, Ulrich, Lanvers, Pia, Sauer, Daniel F., Wittwer, Malte, Dhoke, Gaurao V., Davari, Mehdi D., Schiffels, Johannes, Schwaneberg, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7839715/
https://www.ncbi.nlm.nih.gov/pubmed/32955127
http://dx.doi.org/10.1002/chem.202003637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7839715/
https://www.ncbi.nlm.nih.gov/pubmed/32955127
http://dx.doi.org/10.1002/chem.202003637

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