Amino‐Supported Palladium Catalyst for Chemo‐ and Stereoselective Domino Reactions

A solid amino‐supported palladium catalyst is used in an oxidative domino reaction for the diastereoselective construction of alkyne‐substituted cyclopentenol compounds. This heterogeneous catalyst exhibits high efficiency and excellent chemoselectivity, as well as good recyclability. The chemoselec...

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Detalles Bibliográficos
Autores principales: Li, Man‐Bo, Yang, Jie, Yang, Ying, Xu, Guo‐Yong, Luo, Gen, Yang, Jianping, Bäckvall, Jan‐E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7839730/
https://www.ncbi.nlm.nih.gov/pubmed/32969105
http://dx.doi.org/10.1002/anie.202011708
Descripción
Sumario:A solid amino‐supported palladium catalyst is used in an oxidative domino reaction for the diastereoselective construction of alkyne‐substituted cyclopentenol compounds. This heterogeneous catalyst exhibits high efficiency and excellent chemoselectivity, as well as good recyclability. The chemoselectivity of the domino reactions was readily controlled by switching the solvent and catalyst. Asymmetric syntheses and an oxidative carbocyclization‐borylation reaction have also been developed based on the heterogeneous palladium catalyst.

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