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Warthin-Like Variant of Papillary Thyroid Carcinoma: An Uncommon Variant

Papillary thyroid carcinoma (PTC) is one of the most common thyroid malignancy with various histologic variants. Acknowledging the correct histological variant of PTC helps to know about the tumor's nature and prognosis. The Warthin-like variant of papillary thyroid (WLPTC), a newly described h...

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Detalles Bibliográficos
Autores principales: Kumar, Tarun, Nigam, Jitendra S, Tewari, Prerna, Jha, Chandan K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7839799/
https://www.ncbi.nlm.nih.gov/pubmed/33520545
http://dx.doi.org/10.7759/cureus.12350
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author Kumar, Tarun
Nigam, Jitendra S
Tewari, Prerna
Jha, Chandan K
author_facet Kumar, Tarun
Nigam, Jitendra S
Tewari, Prerna
Jha, Chandan K
author_sort Kumar, Tarun
collection PubMed
description Papillary thyroid carcinoma (PTC) is one of the most common thyroid malignancy with various histologic variants. Acknowledging the correct histological variant of PTC helps to know about the tumor's nature and prognosis. The Warthin-like variant of papillary thyroid (WLPTC), a newly described histologic variant of PTC, is relatively uncommon. A 16-year-old female presented with complaints of painful thyroid swelling for two years. Fine needle aspiration cytology (FNAC) from the lobes showed lymphocytic thyroiditis features with Hurthle cell change. Sections from the left lobe revealed a diagnosis of a Warthin‑like variant of PTC without nodal metastasis. WLPTC is a rare variant having a favorable outcome due to the absence of lymph node metastasis, extra-thyroidal extension, and a low recurrence rate. The correct cytological and histomorphological features are of utmost importance to render the diagnosis of WLPTC for better management.
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spelling pubmed-78397992021-01-29 Warthin-Like Variant of Papillary Thyroid Carcinoma: An Uncommon Variant Kumar, Tarun Nigam, Jitendra S Tewari, Prerna Jha, Chandan K Cureus Pathology Papillary thyroid carcinoma (PTC) is one of the most common thyroid malignancy with various histologic variants. Acknowledging the correct histological variant of PTC helps to know about the tumor's nature and prognosis. The Warthin-like variant of papillary thyroid (WLPTC), a newly described histologic variant of PTC, is relatively uncommon. A 16-year-old female presented with complaints of painful thyroid swelling for two years. Fine needle aspiration cytology (FNAC) from the lobes showed lymphocytic thyroiditis features with Hurthle cell change. Sections from the left lobe revealed a diagnosis of a Warthin‑like variant of PTC without nodal metastasis. WLPTC is a rare variant having a favorable outcome due to the absence of lymph node metastasis, extra-thyroidal extension, and a low recurrence rate. The correct cytological and histomorphological features are of utmost importance to render the diagnosis of WLPTC for better management. Cureus 2020-12-28 /pmc/articles/PMC7839799/ /pubmed/33520545 http://dx.doi.org/10.7759/cureus.12350 Text en Copyright © 2020, Kumar et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pathology
Kumar, Tarun
Nigam, Jitendra S
Tewari, Prerna
Jha, Chandan K
Warthin-Like Variant of Papillary Thyroid Carcinoma: An Uncommon Variant
title Warthin-Like Variant of Papillary Thyroid Carcinoma: An Uncommon Variant
title_full Warthin-Like Variant of Papillary Thyroid Carcinoma: An Uncommon Variant
title_fullStr Warthin-Like Variant of Papillary Thyroid Carcinoma: An Uncommon Variant
title_full_unstemmed Warthin-Like Variant of Papillary Thyroid Carcinoma: An Uncommon Variant
title_short Warthin-Like Variant of Papillary Thyroid Carcinoma: An Uncommon Variant
title_sort warthin-like variant of papillary thyroid carcinoma: an uncommon variant
topic Pathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7839799/
https://www.ncbi.nlm.nih.gov/pubmed/33520545
http://dx.doi.org/10.7759/cureus.12350
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