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A systemically deliverable Vaccinia virus with increased capacity for intertumoral and intratumoral spread effectively treats pancreatic cancer

BACKGROUND: Pancreatic cancer remains one of the most lethal cancers and is refractory to immunotherapeutic interventions. Oncolytic viruses are a promising new treatment option, but current platforms demonstrate limited efficacy, especially for inaccessible and metastatic cancers that require syste...

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Detalles Bibliográficos
Autores principales:	Marelli, Giulia, Chard Dunmall, Louisa S, Yuan, Ming, Di Gioia, Carmela, Miao, Jinxin, Cheng, Zhenguo, Zhang, Zhongxian, Liu, Peng, Ahmed, Jahangir, Gangeswaran, Rathi, Lemoine, Nicholas, Wang, Yaohe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Oncolytic and Local Immunotherapy
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7839893/ https://www.ncbi.nlm.nih.gov/pubmed/33500259 http://dx.doi.org/10.1136/jitc-2020-001624

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