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Targeted temperature management at 33°C or 36℃ induces equivalent myocardial protection by inhibiting HMGB1 release in myocardial ischemia/reperfusion injury

Acute myocardial infarction (AMI) is lethal and causes myocardial necrosis via time-dependent ischemia due to prolonged occlusion of the infarct-related artery. No effective therapy or potential therapeutic targets can prevent myocardial ischemia/reperfusion (I/R) injury. Targeted temperature manage...

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Detalles Bibliográficos
Autores principales: Beom, Jin Ho, Kim, Ju Hee, Seo, Jeho, Lee, Jung Ho, Chung, Yong Eun, Chung, Hyun Soo, Chung, Sung Phil, Kim, Chul Hoon, You, Je Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840046/
https://www.ncbi.nlm.nih.gov/pubmed/33503060
http://dx.doi.org/10.1371/journal.pone.0246066