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Fibrillin-1–enriched microenvironment drives endothelial injury and vascular rarefaction in chronic kidney disease
Endothelial cell injury leading to microvascular rarefaction is a characteristic feature of chronic kidney disease (CKD). However, the mechanism underlying endothelial cell dropout is poorly defined. Here, we show a central role of the extracellular microenvironment in controlling endothelial cell s...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for the Advancement of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840119/ https://www.ncbi.nlm.nih.gov/pubmed/33571112 http://dx.doi.org/10.1126/sciadv.abc7170 |