Anti–Na(+)/K(+)-ATPase immunotherapy ameliorates α-synuclein pathology through activation of Na(+)/K(+)-ATPase α1–dependent autophagy

Na(+)/K(+)-ATPase (NKA) plays important roles in maintaining cellular homeostasis. Conversely, reduced NKA activity has been reported in aging and neurodegenerative diseases. However, little is known about the function of NKA in the pathogenesis of Parkinson’s disease (PD). Here, we report that redu...

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Detalles Bibliográficos
Autores principales: Cao, Lei, Xiong, Siping, Wu, Zhiyuan, Ding, Lei, Zhou, Yebo, Sun, Haijian, Zhu, Mengyuan, Lee, Wei Thye, Nie, Xiaowei, Bian, Jin-Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840131/
https://www.ncbi.nlm.nih.gov/pubmed/33571110
http://dx.doi.org/10.1126/sciadv.abc5062

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