Involuntary Movements Following Administration of Hydroxychloroquine for COVID-19 Pneumonia

Hydroxychloroquine (HCQ) has been used as an investigational drug for patients with moderate to severe coronavirus disease 2019 (COVID-19). There have been concerns of potential harms from side effects of the drug. We present a case of a 38-year-old male who was started on HCQ for COVID-19 pneumonia...

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Autores principales: Fernando, Emmaline Zantua, Yu, Jeryl Ritzi Tan, Santos, Salvador Miclat Abad, Jamora, Roland Dominic Go
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Movement Disorder Society 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840242/
https://www.ncbi.nlm.nih.gov/pubmed/33278866
http://dx.doi.org/10.14802/jmd.20091
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author Fernando, Emmaline Zantua
Yu, Jeryl Ritzi Tan
Santos, Salvador Miclat Abad
Jamora, Roland Dominic Go
author_facet Fernando, Emmaline Zantua
Yu, Jeryl Ritzi Tan
Santos, Salvador Miclat Abad
Jamora, Roland Dominic Go
author_sort Fernando, Emmaline Zantua
collection PubMed
description Hydroxychloroquine (HCQ) has been used as an investigational drug for patients with moderate to severe coronavirus disease 2019 (COVID-19). There have been concerns of potential harms from side effects of the drug. We present a case of a 38-year-old male who was started on HCQ for COVID-19 pneumonia. He was referred for evaluation of myoclonus of all extremities, which resolved after discontinuation of HCQ. The involuntary movements were first reported after the initiation of HCQ, persisted despite improvement in inflammatory and radiologic parameters and eventually resolved after HCQ discontinuation. This supports a possible causality related to adverse drug reactions from HCQ that have not been commonly reported.
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spelling pubmed-78402422021-02-05 Involuntary Movements Following Administration of Hydroxychloroquine for COVID-19 Pneumonia Fernando, Emmaline Zantua Yu, Jeryl Ritzi Tan Santos, Salvador Miclat Abad Jamora, Roland Dominic Go J Mov Disord Case Report Hydroxychloroquine (HCQ) has been used as an investigational drug for patients with moderate to severe coronavirus disease 2019 (COVID-19). There have been concerns of potential harms from side effects of the drug. We present a case of a 38-year-old male who was started on HCQ for COVID-19 pneumonia. He was referred for evaluation of myoclonus of all extremities, which resolved after discontinuation of HCQ. The involuntary movements were first reported after the initiation of HCQ, persisted despite improvement in inflammatory and radiologic parameters and eventually resolved after HCQ discontinuation. This supports a possible causality related to adverse drug reactions from HCQ that have not been commonly reported. The Korean Movement Disorder Society 2021-01 2020-12-07 /pmc/articles/PMC7840242/ /pubmed/33278866 http://dx.doi.org/10.14802/jmd.20091 Text en Copyright © 2021 The Korean Movement Disorder Society This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Fernando, Emmaline Zantua
Yu, Jeryl Ritzi Tan
Santos, Salvador Miclat Abad
Jamora, Roland Dominic Go
Involuntary Movements Following Administration of Hydroxychloroquine for COVID-19 Pneumonia
title Involuntary Movements Following Administration of Hydroxychloroquine for COVID-19 Pneumonia
title_full Involuntary Movements Following Administration of Hydroxychloroquine for COVID-19 Pneumonia
title_fullStr Involuntary Movements Following Administration of Hydroxychloroquine for COVID-19 Pneumonia
title_full_unstemmed Involuntary Movements Following Administration of Hydroxychloroquine for COVID-19 Pneumonia
title_short Involuntary Movements Following Administration of Hydroxychloroquine for COVID-19 Pneumonia
title_sort involuntary movements following administration of hydroxychloroquine for covid-19 pneumonia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840242/
https://www.ncbi.nlm.nih.gov/pubmed/33278866
http://dx.doi.org/10.14802/jmd.20091
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