Quantitative image analysis of microbial communities with BiofilmQ

Biofilms are microbial communities that represent a highly abundant form of microbial life on Earth. Inside biofilms, phenotypic and genotypic variations occur in three-dimensional space and time; microscopy and quantitative image analysis are therefore crucial for elucidating their functions. Here,...

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Detalles Bibliográficos
Autores principales: Hartmann, Raimo, Jeckel, Hannah, Jelli, Eric, Singh, Praveen K., Vaidya, Sanika, Bayer, Miriam, Rode, Daniel K. H., Vidakovic, Lucia, Díaz-Pascual, Francisco, Fong, Jiunn C. N., Dragoš, Anna, Lamprecht, Olga, Thöming, Janne G., Netter, Niklas, Häussler, Susanne, Nadell, Carey D., Sourjik, Victor, Kovács, Ákos T., Yildiz, Fitnat H., Drescher, Knut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840502/
https://www.ncbi.nlm.nih.gov/pubmed/33398098
http://dx.doi.org/10.1038/s41564-020-00817-4
Descripción
Sumario:Biofilms are microbial communities that represent a highly abundant form of microbial life on Earth. Inside biofilms, phenotypic and genotypic variations occur in three-dimensional space and time; microscopy and quantitative image analysis are therefore crucial for elucidating their functions. Here, we present BiofilmQ—a comprehensive image cytometry software tool for the automated and high-throughput quantification, analysis and visualization of numerous biofilm-internal and whole-biofilm properties in three-dimensional space and time.

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