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Lateral habenula dysfunctions in Tm4sf2(−/y) mice model for neurodevelopmental disorder
Mutations in the TM4SF2 gene, which encodes TSPAN7, cause a severe form of intellectual disability (ID) often comorbid with autism spectrum disorder (ASD). Recently, we found that TM4SF2 loss in mice affects cognition. Here, we report that Tm4sf2(−/y) mice, beyond an ID-like phenotype, display alter...
Autores principales: | Murru, Luca, Ponzoni, Luisa, Longatti, Anna, Mazzoleni, Sara, Giansante, Giorgia, Bassani, Silvia, Sala, Mariaelvina, Passafaro, Maria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840593/ https://www.ncbi.nlm.nih.gov/pubmed/33227491 http://dx.doi.org/10.1016/j.nbd.2020.105189 |
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