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Allopregnanolone Decreases Evoked Dopamine Release Differently in Rats by Sex and Estrous Stage

Mesolimbic dopamine transmission is dysregulated in multiple psychiatric disorders, including addiction. Previous studies found that the endogenous GABAergic steroid (3α,5α)-3-hydroxy-5-pregnan-20-one (allopregnanolone) modulates dopamine levels in the nucleus accumbens and prefrontal cortex. As all...

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Detalles Bibliográficos
Autores principales:	Dornellas, Ana Paula S., Macedo, Giovana C., McFarland, Minna H., Gómez-A, Alexander, O’Buckley, Todd K., Da Cunha, Claudio, Morrow, A. Leslie, Robinson, Donita L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840599/ https://www.ncbi.nlm.nih.gov/pubmed/33519475 http://dx.doi.org/10.3389/fphar.2020.608887

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