Local Stabilization of Hypoxia-Inducible Factor-1α Controls Intestinal Inflammation via Enhanced Gut Barrier Function and Immune Regulation

Intestinal epithelial cells are adapted in mucosal hypoxia and hypoxia-inducible factors in these cells can fortify barrier integrity to support mucosal tissue healing. Here we investigated whether hypoxia-related pathways could be proposed as potential therapeutic targets for inflammatory bowel dis...

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Detalles Bibliográficos
Autores principales: Kim, Young-In, Yi, Eun-Je, Kim, Young-Dae, Lee, A Reum, Chung, Jiwoung, Ha, Hae Chan, Cho, Joong Myung, Kim, Seong-Ryeol, Ko, Hyun-Jeong, Cheon, Jae-Hee, Hong, Yong Rae, Chang, Sun-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840603/
https://www.ncbi.nlm.nih.gov/pubmed/33519819
http://dx.doi.org/10.3389/fimmu.2020.609689

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840603/
https://www.ncbi.nlm.nih.gov/pubmed/33519819
http://dx.doi.org/10.3389/fimmu.2020.609689

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