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Visual function deficits in eyes with resolved endophthalmitis

To evaluate the changes in functional vision in patients with resolved endophthalmitis. This was a cross-sectional study. The study included 20 patients with resolved endophthalmitis and best-corrected visual acuity of 20/100 or better. Visual acuity (VA), contrast threshold (CT), red/green (RG) and...

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Autores principales: Hathibelagal, Amithavikram R., Mulani, Yasmeen, Dave, Vivek Pravin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840664/
https://www.ncbi.nlm.nih.gov/pubmed/33504844
http://dx.doi.org/10.1038/s41598-021-81530-y
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author Hathibelagal, Amithavikram R.
Mulani, Yasmeen
Dave, Vivek Pravin
author_facet Hathibelagal, Amithavikram R.
Mulani, Yasmeen
Dave, Vivek Pravin
author_sort Hathibelagal, Amithavikram R.
collection PubMed
description To evaluate the changes in functional vision in patients with resolved endophthalmitis. This was a cross-sectional study. The study included 20 patients with resolved endophthalmitis and best-corrected visual acuity of 20/100 or better. Visual acuity (VA), contrast threshold (CT), red/green (RG) and yellow/blue (YB) colour vision and 15 Hz flicker modulation threshold (FMT) were assessed using standard psychophysical techniques. The median age was 54 years. The median visual acuity was 0.27 (~ 20/40—Snellen Equivalent) ((interquartile range [IQR]), 0.30) logMAR). The median log contrast threshold (CT) was − 1.13 (IQR, 0.36) log units (normative value for age-matched CT: − 1.61 log units). The median red/green (RG) and yellow/blue (YB) thresholds were 11.52 (IQR, 26.19) and 9.45 (IQR, 16.20) CAD units respectively, which were at least 5 times higher than age-matched normative RG and YB thresholds. The median central cone- mediated FMT was 17.64% (IQR, 23.40%), which was much higher compared to age-matched FMT (5.48% [IQR, 3.47]). Linear regression revealed significant relationship between contrast thresholds and foveal thickness (y = 0.001x−1.47, R(2) = 0.20, p = 0.048). Though endophthalmitis may resolve with a good visual acuity, deficits in visual functions like chromatic discrimination, cone-mediated flicker and contrast sensitivity persist.
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spelling pubmed-78406642021-01-28 Visual function deficits in eyes with resolved endophthalmitis Hathibelagal, Amithavikram R. Mulani, Yasmeen Dave, Vivek Pravin Sci Rep Article To evaluate the changes in functional vision in patients with resolved endophthalmitis. This was a cross-sectional study. The study included 20 patients with resolved endophthalmitis and best-corrected visual acuity of 20/100 or better. Visual acuity (VA), contrast threshold (CT), red/green (RG) and yellow/blue (YB) colour vision and 15 Hz flicker modulation threshold (FMT) were assessed using standard psychophysical techniques. The median age was 54 years. The median visual acuity was 0.27 (~ 20/40—Snellen Equivalent) ((interquartile range [IQR]), 0.30) logMAR). The median log contrast threshold (CT) was − 1.13 (IQR, 0.36) log units (normative value for age-matched CT: − 1.61 log units). The median red/green (RG) and yellow/blue (YB) thresholds were 11.52 (IQR, 26.19) and 9.45 (IQR, 16.20) CAD units respectively, which were at least 5 times higher than age-matched normative RG and YB thresholds. The median central cone- mediated FMT was 17.64% (IQR, 23.40%), which was much higher compared to age-matched FMT (5.48% [IQR, 3.47]). Linear regression revealed significant relationship between contrast thresholds and foveal thickness (y = 0.001x−1.47, R(2) = 0.20, p = 0.048). Though endophthalmitis may resolve with a good visual acuity, deficits in visual functions like chromatic discrimination, cone-mediated flicker and contrast sensitivity persist. Nature Publishing Group UK 2021-01-27 /pmc/articles/PMC7840664/ /pubmed/33504844 http://dx.doi.org/10.1038/s41598-021-81530-y Text en © The Author(s) 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Hathibelagal, Amithavikram R.
Mulani, Yasmeen
Dave, Vivek Pravin
Visual function deficits in eyes with resolved endophthalmitis
title Visual function deficits in eyes with resolved endophthalmitis
title_full Visual function deficits in eyes with resolved endophthalmitis
title_fullStr Visual function deficits in eyes with resolved endophthalmitis
title_full_unstemmed Visual function deficits in eyes with resolved endophthalmitis
title_short Visual function deficits in eyes with resolved endophthalmitis
title_sort visual function deficits in eyes with resolved endophthalmitis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840664/
https://www.ncbi.nlm.nih.gov/pubmed/33504844
http://dx.doi.org/10.1038/s41598-021-81530-y
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