High-throughput toxicogenomic screening of chemicals in the environment using metabolically competent hepatic cell cultures

The ToxCast in vitro screening program has provided concentration-response bioactivity data across more than a thousand assay endpoints for thousands of chemicals found in our environment and commerce. However, most ToxCast screening assays have evaluated individual biological targets in cancer cell...

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Detalles Bibliográficos
Autores principales: Franzosa, Jill A., Bonzo, Jessica A., Jack, John, Baker, Nancy C., Kothiya, Parth, Witek, Rafal P., Hurban, Patrick, Siferd, Stephen, Hester, Susan, Shah, Imran, Ferguson, Stephen S., Houck, Keith A., Wambaugh, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840683/
https://www.ncbi.nlm.nih.gov/pubmed/33504769
http://dx.doi.org/10.1038/s41540-020-00166-2

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