Cargando…

MicroRNA-200a Suppresses Cell Invasion and Migration by Directly Targeting GAB1 in Hepatocellular Carcinoma

MicroRNA-200a (miR-200a) is frequently downregulated in most cancer types and plays an important role in carcinogenesis and cancer progression. In this study, we determined that miR-200a was downregulated in hepatocellular carcinoma (HCC) tissues and cell lines, consistent with the results of our pr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Jianlin, Song, Wenjie, Shen, Weiwei, Yang, Xisheng, Sun, Wei, Qu, Sshibin, Shang, Runze, Ma, Ben, Pu, Meng, Tao, Kaishan, Dou, Kefeng, Li, Haimin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cognizant Communication Corporation 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840785/ https://www.ncbi.nlm.nih.gov/pubmed/28081727 http://dx.doi.org/10.3727/096504016X14685034103798

Ejemplares similares

Downregulation of CENPK suppresses hepatocellular carcinoma malignant progression through regulating YAP1
por: Wang, Jianlin, et al.
Publicado: (2019)

MicroRNA-150 suppresses cell proliferation and metastasis in hepatocellular carcinoma by inhibiting the GAB1-ERK axis
por: Sun, Wei, et al.
Publicado: (2016)

MicroRNA-200a suppresses metastatic potential of side population cells in human hepatocellular carcinoma by decreasing ZEB2
por: Yang, Xisheng, et al.
Publicado: (2015)

Silencing of CDCA5 inhibits cancer progression and serves as a prognostic biomarker for hepatocellular carcinoma
por: Wang, Jianlin, et al.
Publicado: (2018)

Superparamagnetic iron oxide nanoparticles modified with polyethylenimine and galactose for siRNA targeted delivery in hepatocellular carcinoma therapy
por: Yang, Zhen, et al.
Publicado: (2018)

Blockade of ARHGAP11A reverses malignant progress via inactivating Rac1B in hepatocellular carcinoma
por: Dai, Bin, et al.
Publicado: (2018)

Knockdown of CD44 inhibits the invasion and metastasis of hepatocellular carcinoma both in vitro and in vivo by reversing epithelial-mesenchymal transition
por: Gao, Yuan, et al.
Publicado: (2015)

Gab2 and Gab3 Redundantly Suppress Colitis by Modulating Macrophage and CD8(+) T-Cell Activation
por: Wang, Zhengqi, et al.
Publicado: (2019)

Gab2 mediates hepatocellular carcinogenesis by integrating multiple signaling pathways
por: Cheng, Jianghong, et al.
Publicado: (2017)

MicroRNAs involved in neoplastic transformation of liver cancer stem cells
por: Li, Ren, et al.
Publicado: (2010)

miR-183-3p suppresses proliferation and migration of keratinocyte in psoriasis by inhibiting GAB1
por: Liu, Ting, et al.
Publicado: (2020)

MicroRNA-485 plays tumour-suppressive roles in colorectal cancer by directly targeting GAB2
por: Li, Jibin, et al.
Publicado: (2022)

Microarray expression profile of circular RNAs in human pancreatic ductal adenocarcinoma
por: Qu, Shibin, et al.
Publicado: (2015)

Down-Regulation of Gab1 Inhibits Cell Proliferation and Migration in Hilar Cholangiocarcinoma
por: Sang, Haiquan, et al.
Publicado: (2013)

The Role of GAB1 in Cancer
por: Pérez-Baena, Manuel Jesús, et al.
Publicado: (2023)

LncRNA-URHC Functions as ceRNA to Regulate DNAJB9 Expression by Competitively Binding to miR-5007-3p in Hepatocellular Carcinoma
por: Niu, Kunwei, et al.
Publicado: (2021)

The emerging landscape of circular RNA in life processes
por: Qu, Shibin, et al.
Publicado: (2016)

Linking Protective GAB2 Variants, Increased Cortical GAB2 Expression and Decreased Alzheimer’s Disease Pathology
por: Zou, Fanggeng, et al.
Publicado: (2013)

Tg737 signaling is required for hypoxia-enhanced invasion and migration of hepatoma cells
por: You, Nan, et al.
Publicado: (2012)

miR-9 and miR-181a Target Gab2 to Inhibit the Proliferation and Migration of Hepatocellular Carcinoma HepG2 Cells
por: Huang, Lantang, et al.
Publicado: (2022)

Long noncoding RNA SLC2A1‐AS1 regulates aerobic glycolysis and progression in hepatocellular carcinoma via inhibiting the STAT3/FOXM1/GLUT1 pathway
por: Shang, Runze, et al.
Publicado: (2020)

Prognostic value of preoperative inflammatory markers in patients with hepatocellular carcinoma who underwent curative resection
por: Wu, Wenlong, et al.
Publicado: (2021)

Gab2 regulates cytoskeletal organization and migration of mammary epithelial cells by modulating RhoA activation
por: Abreu, Maria Teresa Herrera, et al.
Publicado: (2011)

Knockdown of Gab1 Inhibits Cellular Proliferation, Migration, and Invasion in Human Oral Squamous Carcinoma Cells
por: Xu, Luyong, et al.
Publicado: (2018)

MicroRNA-218 inhibits tumor angiogenesis of human renal cell carcinoma by targeting GAB2
por: Mu, Lijun, et al.
Publicado: (2020)

MicroRNA-218 inhibits tumor angiogenesis of human renal cell carcinoma by targeting GAB2
por: Mu, Lijun, et al.
Publicado: (2022)

The mRNA of TCTP functions as a sponge to maintain homeostasis of TCTP protein levels in hepatocellular carcinoma
por: Liu, Wei, et al.
Publicado: (2020)

MicroRNA‐769‐5p suppresses cell growth and migration via targeting NUSAP1 in bladder cancer
por: Chen, Yifan, et al.
Publicado: (2020)

Downregulation of miR-200a Induces EMT Phenotypes and CSC-like Signatures through Targeting the β-catenin Pathway in Hepatic Oval Cells
por: Liu, Jie, et al.
Publicado: (2013)

Research Progress on Long Noncoding RNAs and N6-Methyladenosine in Hepatocellular Carcinoma
por: Zhang, Wenjie, et al.
Publicado: (2022)

Gab Adapter Proteins as Therapeutic Targets for Hematologic Disease
por: Verma, Sheetal, et al.
Publicado: (2012)

Gab Docking Proteins in Cardiovascular Disease, Cancer, and Inflammation
por: Nakaoka, Yoshikazu, et al.
Publicado: (2013)

Interference of PTK6/GAB1 signaling inhibits cell proliferation, invasion, and migration of cervical cancer cells
por: Li, Juan, et al.
Publicado: (2022)

Circulating microRNA-200 Family as Diagnostic Marker in Hepatocellular Carcinoma
por: Dhayat, Sameer A., et al.
Publicado: (2015)

The mTOR inhibition in concurrence with ERK1/2 activation is involved in excessive autophagy induced by glycyrrhizin in hepatocellular carcinoma
por: Zhang, Xuan, et al.
Publicado: (2017)

Activation of gab cluster transcription in Bacillus thuringiensis by γ-aminobutyric acid or succinic semialdehyde is mediated by the Sigma 54-dependent transcriptional activator GabR
por: Peng, Qi, et al.
Publicado: (2014)

MicroRNA-200a suppresses the Wnt/β-catenin signaling pathway by interacting with β-catenin
por: SU, JUAN, et al.
Publicado: (2011)

Function, regulation and pathological roles of the Gab/DOS docking proteins
por: Wöhrle, Franziska U, et al.
Publicado: (2009)

Structure and function of Gab2 and its role in cancer (Review)
por: DING, CHEN-BO, et al.
Publicado: (2015)

MicroRNA-200a suppresses migration and invasion and enhances the radiosensitivity of NSCLC cells by inhibiting the HGF/c-Met signaling pathway
por: Du, Menghua, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_vgc5ea33di69kjmibhqcrj8sgg