Structures of the archaerhodopsin-3 transporter reveal that disordering of internal water networks underpins receptor sensitization

Many transmembrane receptors have a desensitized state, in which they are unable to respond to external stimuli. The family of microbial rhodopsin proteins includes one such group of receptors, whose inactive or dark-adapted (DA) state is established in the prolonged absence of light. Here, we prese...

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Detalles Bibliográficos
Autores principales: Bada Juarez, Juan F., Judge, Peter J., Adam, Suliman, Axford, Danny, Vinals, Javier, Birch, James, Kwan, Tristan O. C., Hoi, Kin Kuan, Yen, Hsin-Yung, Vial, Anthony, Milhiet, Pierre-Emmanuel, Robinson, Carol V., Schapiro, Igor, Moraes, Isabel, Watts, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840839/
https://www.ncbi.nlm.nih.gov/pubmed/33504778
http://dx.doi.org/10.1038/s41467-020-20596-0

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