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Architecture of the Tuberous Sclerosis Protein Complex

The Tuberous Sclerosis Complex (TSC) protein complex (TSCC), comprising TSC1, TSC2, and TBC1D7, is widely recognised as a key integration hub for cell growth and intracellular stress signals upstream of the mammalian target of rapamycin complex 1 (mTORC1). The TSCC negatively regulates mTORC1 by act...

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Detalles Bibliográficos
Autores principales:	Ramlaul, Kailash, Fu, Wencheng, Li, Hua, de Martin Garrido, Natàlia, He, Lin, Trivedi, Manjari, Cui, Wei, Aylett, Christopher H.S., Wu, Geng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840889/ https://www.ncbi.nlm.nih.gov/pubmed/33307091 http://dx.doi.org/10.1016/j.jmb.2020.166743

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