Cardiac-specific microRNA-125b deficiency induces perinatal death and cardiac hypertrophy

MicroRNA-125b, the first microRNA to be identified, is known to promote cardiomyocyte maturation from embryonic stem cells; however, its physiological role remains unclear. To investigate the role of miR-125b in cardiovascular biology, cardiac-specific miR-125b-1 knockout mice were generated. We fou...

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Detalles Bibliográficos
Autores principales: Chen, Chen-Yun, Lee, Desy S., Choong, Oi Kuan, Chang, Sheng-Kai, Hsu, Tien, Nicholson, Martin W., Liu, Li-Wei, Lin, Po-Ju, Ruan, Shu-Chian, Lin, Shu-Wha, Hu, Chung-Yi, Hsieh, Patrick C. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840921/
https://www.ncbi.nlm.nih.gov/pubmed/33504864
http://dx.doi.org/10.1038/s41598-021-81700-y

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