Examining the In Vitro Efficacy of the IAP Antagonist Birinapant as a Single Agent or in Combination With Dacarbazine to Induce Melanoma Cell Death

Antagonists of inhibitors of apoptosis proteins (IAPs), alone or in combination with genotoxic therapeutics, have been shown to efficiently induce cell death in various solid tumors. The IAP antagonist birinapant is currently being tested in phase II clinical trials. We herein aimed to investigate t...

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Detalles Bibliográficos
Autores principales: Vetma, Vesna, Rožanc, Jan, Charles, Emilie M., Hellwig, Christian T., Alexopoulos, Leonidas G., Rehm, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cognizant Communication Corporation 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841063/
https://www.ncbi.nlm.nih.gov/pubmed/28337955
http://dx.doi.org/10.3727/096504017X14897145996933

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841063/
https://www.ncbi.nlm.nih.gov/pubmed/28337955
http://dx.doi.org/10.3727/096504017X14897145996933

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