Cargando…

3-Phosphoinositide Dependent Protein Kinase-1 (PDK-1) Promotes Migration and Invasion in Gastric Cancer Cells Through Activating the NF-κB Pathway

Gastric cancer (GC) is one of the most common cancers and the second leading cause of cancer deaths in the world. Many factors have been reported regarding the progression and development of GC. In this study, we aimed to investigate the correlation of 3-phosphoinositide dependent protein kinase-1 (...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Ning, He, Changyu, Zhu, Bohui, Jiang, Jinling, Chen, Yiwen, Ma, Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cognizant Communication Corporation 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841078/ https://www.ncbi.nlm.nih.gov/pubmed/28109078 http://dx.doi.org/10.3727/096504017X14845839228545

Ejemplares similares

3-Phosphoinositide-dependent Protein Kinase-1 (PDK1) promotes invasion and activation of matrix metalloproteinases
por: Xie, Zhihui, et al.
Publicado: (2006)

Serine/Threonine Kinase 3-Phosphoinositide-Dependent Protein Kinase-1 (PDK1) as a Key Regulator of Cell Migration and Cancer Dissemination
por: Di Blasio, Laura, et al.
Publicado: (2017)

Activation of the essential kinase PDK1 by phosphoinositide-driven trans-autophosphorylation
por: Levina, Aleksandra, et al.
Publicado: (2022)

Molecular characterization of the Haemonchus contortus phosphoinositide-dependent protein kinase-1 gene (Hc-pdk-1)
por: Li, Fa-Cai, et al.
Publicado: (2016)

Phosphoinositide-dependent protein kinase-1 (PDK1)-independent activation of the protein kinase C substrate, protein kinase D
por: Wood, C. David, et al.
Publicado: (2007)

Knockdown of phosphoinositide-dependent kinase 1 (PDK1) inhibits fibrosis and inflammation in lipopolysaccharide-induced acute lung injury rat model by attenuating NF-κB/p65 pathway activation
por: Yang, Keke, et al.
Publicado: (2021)

Helicobacter pylori modulates host cell survival regulation through the serine-threonine kinase, 3-phosphoinositide dependent kinase 1 (PDK-1)
por: King, Charles C., et al.
Publicado: (2015)

Phosphoinositide-dependent kinase 1 integrates T cell receptor and CD28 co-receptor signaling to effect NF-κB induction and T cell activation
por: Park, Sung-Gyoo, et al.
Publicado: (2009)

Phosphoinositide-dependent kinase 1 controls migration and malignant transformation but not cell growth and proliferation in PTEN-null lymphocytes
por: Finlay, David K., et al.
Publicado: (2009)

PDK1 induces JunB, EMT, cell migration and invasion in human gallbladder cancer
por: Lian, Shixian, et al.
Publicado: (2015)

Essential role of PDK1 in regulating endothelial cell migration
por: Primo, Luca, et al.
Publicado: (2007)

Notch-induced T cell development requires phosphoinositide-dependent kinase 1
por: Kelly, April P, et al.
Publicado: (2007)

3-Phosphoinositide-dependent kinase 1 drives acquired resistance to osimertinib
por: Meraz, Ismail M., et al.
Publicado: (2023)

Suppression of PMA-induced tumor cell invasion and migration by ginsenoside Rg1 via the inhibition of NF-κB-dependent MMP-9 expression
por: LI, LI, et al.
Publicado: (2014)

CD44 regulates prostate cancer proliferation, invasion and migration via PDK1 and PFKFB4
por: Li, Wei, et al.
Publicado: (2017)

The 3-Phosphoinositide-Dependent Protein Kinase 1 Inhibits Rod Photoreceptor Development
por: Xing, Tiaosi, et al.
Publicado: (2018)

Phosphoinositide-3-Kinase Is the Primary Mediator of Phosphoinositide-Dependent Inhibition in Mammalian Olfactory Receptor Neurons
por: Ukhanov, Kirill, et al.
Publicado: (2016)

Elastic network model of allosteric regulation in protein kinase PDK1
por: Williams, Gareth
Publicado: (2010)

The kinase PDK1 is critical for promoting T follicular helper cell differentiation
por: Sun, Zhen, et al.
Publicado: (2021)

NFκB-Mediated Expression of Phosphoinositide 3-Kinase δ Is Critical for Mesenchymal Transition in Retinal Pigment Epithelial Cells
por: Han, Haote, et al.
Publicado: (2023)

S6K1-mediated phosphorylation of PDK1 impairs AKT kinase activity and oncogenic functions
por: Jiang, Qiwei, et al.
Publicado: (2022)

Phosphoinositide-dependent kinase 1 targets protein kinase A in a pathway that regulates interleukin 4
por: Nirula, Ajay, et al.
Publicado: (2006)

3-Phosphoinositide-dependent protein kinase-1 as an emerging target in the management of breast cancer
por: Fyffe, Chanse, et al.
Publicado: (2013)

Preclinical validation of 3-phosphoinositide-dependent protein kinase 1 inhibition in pancreatic cancer
por: Emmanouilidi, Aikaterini, et al.
Publicado: (2019)

Author Correction: 3-Phosphoinositide-dependent kinase 1 drives acquired resistance to osimertinib
por: Meraz, Ismail M., et al.
Publicado: (2023)

The Kinase PDK1 Is Essential for B-Cell Receptor Mediated Survival Signaling
por: Park, Sung-Gyoo, et al.
Publicado: (2013)

The 3-phosphoinositide–dependent protein kinase 1 is an essential upstream activator of protein kinase A in malaria parasites
por: Hitz, Eva, et al.
Publicado: (2021)

PKCθ-Mediated PDK1 Phosphorylation Enhances T Cell Activation by Increasing PDK1 Stability
por: Kang, Jung-Ah, et al.
Publicado: (2017)

The Role of Phosphoinositide 3-Kinases in Neutrophil Migration in 3D Collagen Gels
por: Martin, Kayleigh J. S., et al.
Publicado: (2015)

Correction: UFM1 suppresses invasive activities of gastric cancer cells by attenuating the expression of PDK1 through PI3K/AKT signaling
por: Lin, Jian-Xian, et al.
Publicado: (2023)

The Landscape of PDK1 in Breast Cancer
por: Wang, Na, et al.
Publicado: (2022)

The tumor suppressor PTEN and the PDK1 kinase regulate formation of the columnar neural epithelium
por: Grego-Bessa, Joaquim, et al.
Publicado: (2016)

STAT3 enhances the constitutive activity of AGC kinases in melanoma by transactivating PDK1
por: Picco, María Elisa, et al.
Publicado: (2019)

Modulation of the substrate specificity of the kinase PDK1 by distinct conformations of the full-length protein*
por: Sacerdoti, Mariana, et al.
Publicado: (2023)

The kinase PDK1 regulates regulatory T cell survival via controlling redox homeostasis
por: Feng, Peiran, et al.
Publicado: (2021)

Protein Kinase Activity of Phosphoinositide 3-Kinase Regulates Cytokine-Dependent Cell Survival
por: Thomas, Daniel, et al.
Publicado: (2013)

Cellular Notch responsiveness is defined by phosphoinositide 3-kinase-dependent signals
por: Mckenzie, Grahame, et al.
Publicado: (2006)

UFM1 suppresses invasive activities of gastric cancer cells by attenuating the expres7sion of PDK1 through PI3K/AKT signaling
por: Lin, Jian-Xian, et al.
Publicado: (2019)

TANK-binding kinase 1 (TBK1) modulates inflammatory hyperalgesia by regulating MAP kinases and NF-κB dependent genes
por: Möser, Christine V., et al.
Publicado: (2015)

Correction: The Role of Phosphoinositide 3-Kinases in Neutrophil Migration in 3D Collagen Gels
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_kvq2fjl5c404k1a45dbj0v5mkh