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miR-92a Inhibits Proliferation and Induces Apoptosis by Regulating Methylenetetrahydrofolate Dehydrogenase 2 (MTHFD2) Expression in Acute Myeloid Leukemia

Aberrant expression of microRNA-92a (miR-92a) has been investigated in various cancers. However, the function and mechanism of miR-92a in acute myeloid leukemia (AML) remain to be elucidated. Our data showed that miR-92a was evidently downregulated and methylenetetrahydrofolate dehydrogenase 2 (MTHF...

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Detalles Bibliográficos
Autores principales: Gu, Yueli, Si, Jinchun, Xiao, Xichun, Tian, Ying, Yang, Shuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cognizant Communication Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841081/
https://www.ncbi.nlm.nih.gov/pubmed/28059050
http://dx.doi.org/10.3727/096504016X14829256525028