Three Combined Treatments, a Novel HDAC Inhibitor OBP-801/YM753, 5-Fluorouracil, and Paclitaxel, Induce G(2) Phase Arrest Through the p38 Pathway in Human Ovarian Cancer Cells

Ovarian cancer is the most lethal disease among gynecological malignancies. More effective therapy is required to counter high recurrence rates and chemotherapy resistance. We investigated the efficacy and molecular mechanisms of three combined treatments (TCTs)—a novel histone deacetylase (HDAC) in...

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Autores principales: Akiyama, Makoto, Sowa, Yoshihiro, Taniguchi, Tomoyuki, Watanabe, Motoki, Yogosawa, Shingo, Kitawaki, Jo, Sakai, Toshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cognizant Communication Corporation 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841106/
https://www.ncbi.nlm.nih.gov/pubmed/28117030
http://dx.doi.org/10.3727/096504017X14850164661097

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