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Integrated Metabolomics and Lipidomics Analysis Reveal Remodeling of Lipid Metabolism and Amino Acid Metabolism in Glucagon Receptor–Deficient Zebrafish

The glucagon receptor (GCGR) is activated by glucagon and is essential for glucose, amino acid, and lipid metabolism of animals. GCGR blockade has been demonstrated to induce hypoglycemia, hyperaminoacidemia, hyperglucagonemia, decreased adiposity, hepatosteatosis, and pancreatic α cells hyperplasia...

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Detalles Bibliográficos
Autores principales:	Bai, Xuanxuan, Jia, Jianxin, Kang, Qi, Fu, Yadong, Zhou, You, Zhong, Yingbin, Zhang, Chao, Li, Mingyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841139/ https://www.ncbi.nlm.nih.gov/pubmed/33520988 http://dx.doi.org/10.3389/fcell.2020.605979

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