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Cdk5rap3 is essential for intestinal Paneth cell development and maintenance

Intestinal Paneth cells are professional exocrine cells that play crucial roles in maintenance of homeostatic microbiome, modulation of mucosal immunity, and support for stem cell self-renewal. Dysfunction of these cells may lead to the pathogenesis of human diseases such as inflammatory bowel disea...

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Detalles Bibliográficos
Autores principales: Quintero, Michaela, Liu, Siyang, Xia, Yanhua, Huang, Yonghong, Zou, Yi, Li, Ge, Hu, Ling, Singh, Nagendra, Blumberg, Richard, Cai, Yafei, Xu, Hong, Li, Honglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841144/
https://www.ncbi.nlm.nih.gov/pubmed/33504792
http://dx.doi.org/10.1038/s41419-021-03401-8