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Connective tissue growth factor promotes chemotaxis of preosteoblasts through integrin α5 and Ras during tensile force-induced intramembranous osteogenesis
In vertebrates, new bone formation via intramembranous osteogenesis is a critical biological event for development, remodeling, and fracture healing of bones. Chemotaxis of osteoblast lineage cells is an essential cellular process in new bone formation. Connective tissue growth factor (CTGF) is know...
Autores principales: | Jiang, Wei, Takeshita, Nobuo, Maeda, Toshihiro, Sogi, Chisumi, Oyanagi, Toshihito, Kimura, Seiji, Yoshida, Michiko, Sasaki, Kiyo, Ito, Arata, Takano-Yamamoto, Teruko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841149/ https://www.ncbi.nlm.nih.gov/pubmed/33504916 http://dx.doi.org/10.1038/s41598-021-82246-9 |
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