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Simultaneous, But Not Consecutive, Combination With Folinate Salts Potentiates 5-Fluorouracil Antitumor Activity In Vitro and In Vivo

The combination of folinate salts to 5-fluoruracil (5-FU)-based schedules is an established clinical routine in the landscape of colorectal cancer treatment. The aim of this study was to investigate the pharmacological differences between the sequential administration of folinate salts (1 h before,...

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Detalles Bibliográficos
Autores principales: Di Paolo, Antonello, Orlandi, Paola, Di Desidero, Teresa, Danesi, Romano, Bocci, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cognizant Communication Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841196/
https://www.ncbi.nlm.nih.gov/pubmed/28109077
http://dx.doi.org/10.3727/096504017X14841698396900