The Inhibitory Effects of HYDAMTIQ, a Novel PARP Inhibitor, on Growth in Human Tumor Cell Lines With Defective DNA Damage Response Pathways

The poly(ADP-ribose) polymerase (PARP) enzymes play a key role in the regulation of cellular processes (e.g., DNA damage repair, genomic stability). It has been shown that PARP inhibitors (PARPIs) are selectively cytotoxic against cells having dysfunctions in genes involved in DNA repair mechanisms...

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Detalles Bibliográficos
Autores principales: Mini, Enrico, Landini, Ida, Lucarini, Laura, Lapucci, Andrea, Napoli, Cristina, Perrone, Gabriele, Tassi, Renato, Masini, Emanuela, Moroni, Flavio, Nobili, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cognizant Communication Corporation 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841208/
https://www.ncbi.nlm.nih.gov/pubmed/28429680
http://dx.doi.org/10.3727/096504017X14926854178616

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841208/
https://www.ncbi.nlm.nih.gov/pubmed/28429680
http://dx.doi.org/10.3727/096504017X14926854178616

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