Extracellular Vesicles in Rheumatoid Arthritis and Systemic Lupus Erythematosus: Functions and Applications

In the last two decades, extracellular vesicles (EVs) have aroused wide interest among researchers in basic and clinical research. EVs, small membrane vesicles are released by almost all kinds of cells into the extracellular environment. According to many recent studies, EVs participate in immunomod...

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Detalles Bibliográficos
Autores principales: Zhang, Bo, Zhao, Ming, Lu, Qianjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841259/
https://www.ncbi.nlm.nih.gov/pubmed/33519800
http://dx.doi.org/10.3389/fimmu.2020.575712
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author Zhang, Bo
Zhao, Ming
Lu, Qianjin
author_facet Zhang, Bo
Zhao, Ming
Lu, Qianjin
author_sort Zhang, Bo
collection PubMed
description In the last two decades, extracellular vesicles (EVs) have aroused wide interest among researchers in basic and clinical research. EVs, small membrane vesicles are released by almost all kinds of cells into the extracellular environment. According to many recent studies, EVs participate in immunomodulation and play an important role in the pathogenesis of autoimmune diseases. In addition, EVs have great potential in the diagnosis and therapy of autoimmune diseases. Here, we reviewed the latest research advances on the functions and mechanisms of EVs and their roles in the pathogenesis, diagnosis, and treatment of rheumatoid arthritis and systemic lupus erythematosus.
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spelling pubmed-78412592021-01-29 Extracellular Vesicles in Rheumatoid Arthritis and Systemic Lupus Erythematosus: Functions and Applications Zhang, Bo Zhao, Ming Lu, Qianjin Front Immunol Immunology In the last two decades, extracellular vesicles (EVs) have aroused wide interest among researchers in basic and clinical research. EVs, small membrane vesicles are released by almost all kinds of cells into the extracellular environment. According to many recent studies, EVs participate in immunomodulation and play an important role in the pathogenesis of autoimmune diseases. In addition, EVs have great potential in the diagnosis and therapy of autoimmune diseases. Here, we reviewed the latest research advances on the functions and mechanisms of EVs and their roles in the pathogenesis, diagnosis, and treatment of rheumatoid arthritis and systemic lupus erythematosus. Frontiers Media S.A. 2021-01-14 /pmc/articles/PMC7841259/ /pubmed/33519800 http://dx.doi.org/10.3389/fimmu.2020.575712 Text en Copyright © 2021 Zhang, Zhao and Lu http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Immunology
Zhang, Bo
Zhao, Ming
Lu, Qianjin
Extracellular Vesicles in Rheumatoid Arthritis and Systemic Lupus Erythematosus: Functions and Applications
title Extracellular Vesicles in Rheumatoid Arthritis and Systemic Lupus Erythematosus: Functions and Applications
title_full Extracellular Vesicles in Rheumatoid Arthritis and Systemic Lupus Erythematosus: Functions and Applications
title_fullStr Extracellular Vesicles in Rheumatoid Arthritis and Systemic Lupus Erythematosus: Functions and Applications
title_full_unstemmed Extracellular Vesicles in Rheumatoid Arthritis and Systemic Lupus Erythematosus: Functions and Applications
title_short Extracellular Vesicles in Rheumatoid Arthritis and Systemic Lupus Erythematosus: Functions and Applications
title_sort extracellular vesicles in rheumatoid arthritis and systemic lupus erythematosus: functions and applications
topic Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841259/
https://www.ncbi.nlm.nih.gov/pubmed/33519800
http://dx.doi.org/10.3389/fimmu.2020.575712
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