CCR2- and Flt3-Dependent Inflammatory Conventional Type 2 Dendritic Cells Are Necessary for the Induction of Adaptive Immunity by the Human Vaccine Adjuvant System AS01

The Adjuvant System AS01 contains monophosphoryl lipid A (MPL) and the saponin QS-21 in a liposomal formulation. AS01 is included in recently developed vaccines against malaria and varicella zoster virus. Like for many other adjuvants, induction of adaptive immunity by AS01 is highly dependent on th...

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Detalles Bibliográficos
Autores principales: Bosteels, Cedric, Fierens, Kaat, De Prijck, Sofie, Van Moorleghem, Justine, Vanheerswynghels, Manon, De Wolf, Caroline, Chalon, Aurélie, Collignon, Catherine, Hammad, Hamida, Didierlaurent, Arnaud M., Lambrecht, Bart N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841299/
https://www.ncbi.nlm.nih.gov/pubmed/33519816
http://dx.doi.org/10.3389/fimmu.2020.606805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841299/
https://www.ncbi.nlm.nih.gov/pubmed/33519816
http://dx.doi.org/10.3389/fimmu.2020.606805

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