Liquid biopsy by combining 5-hydroxymethylcytosine signatures of plasma cell-free DNA and protein biomarkers for diagnosis and prognosis of hepatocellular carcinoma

BACKGROUND: Liquid biopsy based on 5-hydroxymethylcytosine (5hmC) signatures of plasma cell-free DNA (cfDNA) originating from tumor cells provides a novel approach for early diagnosis in hepatocellular carcinoma (HCC). Here, we sought to develop a reliable model using cfDNA 5hmC signatures and prote...

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Detalles Bibliográficos
Autores principales: Cai, Z., Zhang, J., He, Y., Xia, L., Dong, X., Chen, G., Zhou, Y., Hu, X., Zhong, S., Wang, Y., Chen, H., Xie, D., Liu, X., Liu, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841321/
https://www.ncbi.nlm.nih.gov/pubmed/33508734
http://dx.doi.org/10.1016/j.esmoop.2020.100021

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