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Optimizing the Intracellular Delivery of Therapeutic Anti-inflammatory TNF-α siRNA to Activated Macrophages Using Lipidoid-Polymer Hybrid Nanoparticles

RNA interference (RNAi) has an unprecedented potential as a therapeutic strategy for reversibly silencing the expression of any gene. Therapeutic delivery of the RNAi mediator, i.e., small interfering RNA (siRNA), can be used to address diseases characterized by gene overexpression, for example infl...

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Detalles Bibliográficos
Autores principales:	Lokras, Abhijeet, Thakur, Aneesh, Wadhwa, Abishek, Thanki, Kaushik, Franzyk, Henrik, Foged, Camilla
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841370/ https://www.ncbi.nlm.nih.gov/pubmed/33520957 http://dx.doi.org/10.3389/fbioe.2020.601155

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