Dissecting Efficacy and Metabolic Characteristic Mechanism of Taxifolin on Renal Fibrosis by Multivariate Approach and Ultra-Performance Liquid Chromatography Coupled With Mass Spectrometry-Based Metabolomics Strategy

Taxifolin (TFN) is an important natural compound with antifibrotic activity; however, its pharmacological mechanism is not clear. In this study, our aim is to gain insight into the effects of TFN and its potential mechanisms in unilateral ureteral obstruction (UUO) animal model using metabolomics ap...

Descripción completa

Detalles Bibliográficos
Autores principales: Ren, Lei, Guo, Hao-Nan, Yang, Jun, Guo, Xiao-Ying, Wei, Ye-Sheng, Yang, Zhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841412/
https://www.ncbi.nlm.nih.gov/pubmed/33519473
http://dx.doi.org/10.3389/fphar.2020.608511

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841412/
https://www.ncbi.nlm.nih.gov/pubmed/33519473
http://dx.doi.org/10.3389/fphar.2020.608511

Ejemplares similares