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Occupational immediate type allergy to soapnut and quillaja bark
A 58-year-old non-atopic chemical worker complained about work-related asthma and rhinoconjunctivitis about 4 years after exposure to quillaja bark and soapnut. Bronchial hyperresponsiveness was demonstrated after withdrawal of medication for 12 hours. Skin prick tests with extracts from quillaja ba...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dustri-Verlag Dr. Karl Feistle
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841414/ https://www.ncbi.nlm.nih.gov/pubmed/33524084 http://dx.doi.org/10.5414/ALX02131E |
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author | Merget, Rolf Raulf, Monika Sander, Ingrid |
author_facet | Merget, Rolf Raulf, Monika Sander, Ingrid |
author_sort | Merget, Rolf |
collection | PubMed |
description | A 58-year-old non-atopic chemical worker complained about work-related asthma and rhinoconjunctivitis about 4 years after exposure to quillaja bark and soapnut. Bronchial hyperresponsiveness was demonstrated after withdrawal of medication for 12 hours. Skin prick tests with extracts from quillaja bark and soapnut from the workplace were positive, but ImmunoCAP was positive only with quillaja bark, probably due to the low protein content of the extract from soapnut. Sensitizations to quillaja bark and soapnut, but not to saponin were demonstrated by immunoblot. An inhalation test with a dosimeter was positive with the soapnut extract. A link between disease and exposure was documented by serial measurements of exhaled nitric oxide at and off work, despite preventive measures. A diagnosis of occupational allergy due to quillaja bark and soapnut was made. Further exposure reduction was recommended. |
format | Online Article Text |
id | pubmed-7841414 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Dustri-Verlag Dr. Karl Feistle |
record_format | MEDLINE/PubMed |
spelling | pubmed-78414142021-01-28 Occupational immediate type allergy to soapnut and quillaja bark Merget, Rolf Raulf, Monika Sander, Ingrid Allergol Select Case Report A 58-year-old non-atopic chemical worker complained about work-related asthma and rhinoconjunctivitis about 4 years after exposure to quillaja bark and soapnut. Bronchial hyperresponsiveness was demonstrated after withdrawal of medication for 12 hours. Skin prick tests with extracts from quillaja bark and soapnut from the workplace were positive, but ImmunoCAP was positive only with quillaja bark, probably due to the low protein content of the extract from soapnut. Sensitizations to quillaja bark and soapnut, but not to saponin were demonstrated by immunoblot. An inhalation test with a dosimeter was positive with the soapnut extract. A link between disease and exposure was documented by serial measurements of exhaled nitric oxide at and off work, despite preventive measures. A diagnosis of occupational allergy due to quillaja bark and soapnut was made. Further exposure reduction was recommended. Dustri-Verlag Dr. Karl Feistle 2021-01-26 /pmc/articles/PMC7841414/ /pubmed/33524084 http://dx.doi.org/10.5414/ALX02131E Text en © Dustri-Verlag Dr. K. Feistle http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Merget, Rolf Raulf, Monika Sander, Ingrid Occupational immediate type allergy to soapnut and quillaja bark |
title | Occupational immediate type allergy to soapnut and quillaja bark |
title_full | Occupational immediate type allergy to soapnut and quillaja bark |
title_fullStr | Occupational immediate type allergy to soapnut and quillaja bark |
title_full_unstemmed | Occupational immediate type allergy to soapnut and quillaja bark |
title_short | Occupational immediate type allergy to soapnut and quillaja bark |
title_sort | occupational immediate type allergy to soapnut and quillaja bark |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841414/ https://www.ncbi.nlm.nih.gov/pubmed/33524084 http://dx.doi.org/10.5414/ALX02131E |
work_keys_str_mv | AT mergetrolf occupationalimmediatetypeallergytosoapnutandquillajabark AT raulfmonika occupationalimmediatetypeallergytosoapnutandquillajabark AT sanderingrid occupationalimmediatetypeallergytosoapnutandquillajabark |