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Cumulative health deficits, APOE genotype, and risk for later-life mild cognitive impairment and dementia
OBJECTIVE: To determine whether health-deficit accumulation is associated with the risks of mild cognitive impairment (MCI) and dementia independently of APOE genotype. METHODS: A frailty index was calculated using the deficit-accumulation approach in participants aged 50 years and older from the Na...
Autores principales: | Ward, David D, Wallace, Lindsay M K, Rockwood, Kenneth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841490/ https://www.ncbi.nlm.nih.gov/pubmed/33188132 http://dx.doi.org/10.1136/jnnp-2020-324081 |
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