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Persistence of SARS-CoV-2 RNA in a male with metabolic syndrome for 72 days: A case report

Coronavirus disease-19 (COVID-19) was first identified in Wuhan, China, and spread gradually throughout the world. There are multiple reports of prolonged viral shedding in people infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); however, such findings have not been documen...

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Autores principales: Islam, SM Rashed Ul, Akther, Tahmina, Sultana, Sharmin, Munshi, Saif Ullah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841660/
https://www.ncbi.nlm.nih.gov/pubmed/33628449
http://dx.doi.org/10.1177/2050313X21989492
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author Islam, SM Rashed Ul
Akther, Tahmina
Sultana, Sharmin
Munshi, Saif Ullah
author_facet Islam, SM Rashed Ul
Akther, Tahmina
Sultana, Sharmin
Munshi, Saif Ullah
author_sort Islam, SM Rashed Ul
collection PubMed
description Coronavirus disease-19 (COVID-19) was first identified in Wuhan, China, and spread gradually throughout the world. There are multiple reports of prolonged viral shedding in people infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); however, such findings have not been documented in Bangladesh. Herein, we present a case of metabolic syndrome that remained positive for SARS-CoV-2 RNA over a prolonged period. On clinical and laboratory examination, the patient was diagnosed with obesity, raised blood pressure, dyslipidemia, and uncontrolled glycemia. However, upon taking appropriate measures and controlling the plasma sugar level, he tested negative for SARS-CoV-2 RNA on the 72nd day since illness onset. We observed that COVID-19 patients with several comorbidities, such as metabolic syndrome, may shed the virus over a prolonged period. Therefore, strict public health measures and isolation rules should be followed by a high-risk population.
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spelling pubmed-78416602021-02-23 Persistence of SARS-CoV-2 RNA in a male with metabolic syndrome for 72 days: A case report Islam, SM Rashed Ul Akther, Tahmina Sultana, Sharmin Munshi, Saif Ullah SAGE Open Med Case Rep Case Report Coronavirus disease-19 (COVID-19) was first identified in Wuhan, China, and spread gradually throughout the world. There are multiple reports of prolonged viral shedding in people infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); however, such findings have not been documented in Bangladesh. Herein, we present a case of metabolic syndrome that remained positive for SARS-CoV-2 RNA over a prolonged period. On clinical and laboratory examination, the patient was diagnosed with obesity, raised blood pressure, dyslipidemia, and uncontrolled glycemia. However, upon taking appropriate measures and controlling the plasma sugar level, he tested negative for SARS-CoV-2 RNA on the 72nd day since illness onset. We observed that COVID-19 patients with several comorbidities, such as metabolic syndrome, may shed the virus over a prolonged period. Therefore, strict public health measures and isolation rules should be followed by a high-risk population. SAGE Publications 2021-01-23 /pmc/articles/PMC7841660/ /pubmed/33628449 http://dx.doi.org/10.1177/2050313X21989492 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Islam, SM Rashed Ul
Akther, Tahmina
Sultana, Sharmin
Munshi, Saif Ullah
Persistence of SARS-CoV-2 RNA in a male with metabolic syndrome for 72 days: A case report
title Persistence of SARS-CoV-2 RNA in a male with metabolic syndrome for 72 days: A case report
title_full Persistence of SARS-CoV-2 RNA in a male with metabolic syndrome for 72 days: A case report
title_fullStr Persistence of SARS-CoV-2 RNA in a male with metabolic syndrome for 72 days: A case report
title_full_unstemmed Persistence of SARS-CoV-2 RNA in a male with metabolic syndrome for 72 days: A case report
title_short Persistence of SARS-CoV-2 RNA in a male with metabolic syndrome for 72 days: A case report
title_sort persistence of sars-cov-2 rna in a male with metabolic syndrome for 72 days: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841660/
https://www.ncbi.nlm.nih.gov/pubmed/33628449
http://dx.doi.org/10.1177/2050313X21989492
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