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Early Outcomes of Adolescent ACL Reconstruction With Hybrid Hamstring Tendon Autograft-Allograft Versus Hamstring Tendon Autograft Alone

BACKGROUND: Small-diameter semitendinosus-gracilis tendon autografts may be encountered intraoperatively during anterior cruciate ligament reconstruction (ACLR); these have been shown to be at increased risk of graft rupture. One option that surgeons have pursued to reduce the theoretical failure ra...

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Autores principales: Heyworth, Benton E., Zheng, Evan T., Vavken, Patrick, Liotta, Elizabeth S., Kramer, Dennis E., Yen, Yi-Meng, Micheli, Lyle J., Kocher, Mininder S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841686/
https://www.ncbi.nlm.nih.gov/pubmed/33553459
http://dx.doi.org/10.1177/2325967120979985
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author Heyworth, Benton E.
Zheng, Evan T.
Vavken, Patrick
Liotta, Elizabeth S.
Kramer, Dennis E.
Yen, Yi-Meng
Micheli, Lyle J.
Kocher, Mininder S.
author_facet Heyworth, Benton E.
Zheng, Evan T.
Vavken, Patrick
Liotta, Elizabeth S.
Kramer, Dennis E.
Yen, Yi-Meng
Micheli, Lyle J.
Kocher, Mininder S.
author_sort Heyworth, Benton E.
collection PubMed
description BACKGROUND: Small-diameter semitendinosus-gracilis tendon autografts may be encountered intraoperatively during anterior cruciate ligament reconstruction (ACLR); these have been shown to be at increased risk of graft rupture. One option that surgeons have pursued to reduce the theoretical failure rate of these smaller-diameter grafts is augmenting them with allograft material, thereby forming a larger-diameter hybrid autograft-allograft construct. PURPOSE/HYPOTHESIS: The purpose of this study was to compare outcomes in adolescent athletes of primary ACLR using a hybrid autologous hamstring tendon and soft tissue allograft construct versus ACLR using small-diameter hamstring tendon autograft. The hypothesis was that the hybrid hamstring autograft-allograft construct would provide superior short-term results. STUDY DESIGN: Cohort study; Level of evidence, 3. METHODS: We performed a retrospective analysis of 47 patients aged between 12 and 20 years who underwent hybrid graft ACLR (mean diameter, 9.1 mm) at a single institution. Electronic medical records including clinic notes, radiographic images, operative notes, and pathology reports were reviewed for study analysis. A control group of 64 patients who underwent small-diameter hamstring reconstruction (mean diameter, 7.1 mm) without allograft supplementation was compiled. Corresponding clinical, radiographic, and surgical characteristics were collected for the control group to allow for comparative analysis. RESULTS: Mean follow-up was 2.7 years for the hybrid cohort and 2.3 years for the control group. Despite a significantly larger mean graft diameter in the hybrid group as compared with the control group (P < .001), no significant difference in retear rate was seen between cohorts (hybrid, 9%; control, 13%; P = .554). Patients with hybrid anterior cruciate ligament constructs also underwent a comparable number of reoperations overall (P = .838). Functionally, all patients with adequate follow-up returned to sports, with no significant difference in time to return to sports between the groups (P = .213). Radiographically, hybrid graft constructs did not undergo a significantly larger degree of tunnel lysis (P = .126). CONCLUSION: A cohort of adolescents with hybrid anterior cruciate ligament grafts was shown to have retear rates and overall clinical results comparable with those of a control group that received small-diameter hamstring tendon autografts alone.
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spelling pubmed-78416862021-02-05 Early Outcomes of Adolescent ACL Reconstruction With Hybrid Hamstring Tendon Autograft-Allograft Versus Hamstring Tendon Autograft Alone Heyworth, Benton E. Zheng, Evan T. Vavken, Patrick Liotta, Elizabeth S. Kramer, Dennis E. Yen, Yi-Meng Micheli, Lyle J. Kocher, Mininder S. Orthop J Sports Med Article BACKGROUND: Small-diameter semitendinosus-gracilis tendon autografts may be encountered intraoperatively during anterior cruciate ligament reconstruction (ACLR); these have been shown to be at increased risk of graft rupture. One option that surgeons have pursued to reduce the theoretical failure rate of these smaller-diameter grafts is augmenting them with allograft material, thereby forming a larger-diameter hybrid autograft-allograft construct. PURPOSE/HYPOTHESIS: The purpose of this study was to compare outcomes in adolescent athletes of primary ACLR using a hybrid autologous hamstring tendon and soft tissue allograft construct versus ACLR using small-diameter hamstring tendon autograft. The hypothesis was that the hybrid hamstring autograft-allograft construct would provide superior short-term results. STUDY DESIGN: Cohort study; Level of evidence, 3. METHODS: We performed a retrospective analysis of 47 patients aged between 12 and 20 years who underwent hybrid graft ACLR (mean diameter, 9.1 mm) at a single institution. Electronic medical records including clinic notes, radiographic images, operative notes, and pathology reports were reviewed for study analysis. A control group of 64 patients who underwent small-diameter hamstring reconstruction (mean diameter, 7.1 mm) without allograft supplementation was compiled. Corresponding clinical, radiographic, and surgical characteristics were collected for the control group to allow for comparative analysis. RESULTS: Mean follow-up was 2.7 years for the hybrid cohort and 2.3 years for the control group. Despite a significantly larger mean graft diameter in the hybrid group as compared with the control group (P < .001), no significant difference in retear rate was seen between cohorts (hybrid, 9%; control, 13%; P = .554). Patients with hybrid anterior cruciate ligament constructs also underwent a comparable number of reoperations overall (P = .838). Functionally, all patients with adequate follow-up returned to sports, with no significant difference in time to return to sports between the groups (P = .213). Radiographically, hybrid graft constructs did not undergo a significantly larger degree of tunnel lysis (P = .126). CONCLUSION: A cohort of adolescents with hybrid anterior cruciate ligament grafts was shown to have retear rates and overall clinical results comparable with those of a control group that received small-diameter hamstring tendon autografts alone. SAGE Publications 2021-01-22 /pmc/articles/PMC7841686/ /pubmed/33553459 http://dx.doi.org/10.1177/2325967120979985 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by-nc-nd/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 License (https://creativecommons.org/licenses/by-nc-nd/4.0/) which permits non-commercial use, reproduction and distribution of the work as published without adaptation or alteration, without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Article
Heyworth, Benton E.
Zheng, Evan T.
Vavken, Patrick
Liotta, Elizabeth S.
Kramer, Dennis E.
Yen, Yi-Meng
Micheli, Lyle J.
Kocher, Mininder S.
Early Outcomes of Adolescent ACL Reconstruction With Hybrid Hamstring Tendon Autograft-Allograft Versus Hamstring Tendon Autograft Alone
title Early Outcomes of Adolescent ACL Reconstruction With Hybrid Hamstring Tendon Autograft-Allograft Versus Hamstring Tendon Autograft Alone
title_full Early Outcomes of Adolescent ACL Reconstruction With Hybrid Hamstring Tendon Autograft-Allograft Versus Hamstring Tendon Autograft Alone
title_fullStr Early Outcomes of Adolescent ACL Reconstruction With Hybrid Hamstring Tendon Autograft-Allograft Versus Hamstring Tendon Autograft Alone
title_full_unstemmed Early Outcomes of Adolescent ACL Reconstruction With Hybrid Hamstring Tendon Autograft-Allograft Versus Hamstring Tendon Autograft Alone
title_short Early Outcomes of Adolescent ACL Reconstruction With Hybrid Hamstring Tendon Autograft-Allograft Versus Hamstring Tendon Autograft Alone
title_sort early outcomes of adolescent acl reconstruction with hybrid hamstring tendon autograft-allograft versus hamstring tendon autograft alone
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841686/
https://www.ncbi.nlm.nih.gov/pubmed/33553459
http://dx.doi.org/10.1177/2325967120979985
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