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Biofilms by bacterial human pathogens: Clinical relevance - development, composition and regulation - therapeutical strategies
Notably, bacterial biofilm formation is increasingly recognized as a passive virulence factor facilitating many infectious disease processes. In this review we will focus on bacterial biofilms formed by human pathogens and highlight their relevance for diverse diseases. Along biofilm composition and...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shared Science Publishers OG
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841849/ https://www.ncbi.nlm.nih.gov/pubmed/33553418 http://dx.doi.org/10.15698/mic2021.02.741 |
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author | Schulze, Adina Mitterer, Fabian Pombo, Joao P. Schild, Stefan |
author_facet | Schulze, Adina Mitterer, Fabian Pombo, Joao P. Schild, Stefan |
author_sort | Schulze, Adina |
collection | PubMed |
description | Notably, bacterial biofilm formation is increasingly recognized as a passive virulence factor facilitating many infectious disease processes. In this review we will focus on bacterial biofilms formed by human pathogens and highlight their relevance for diverse diseases. Along biofilm composition and regulation emphasis is laid on the intensively studied biofilms of Vibrio cholerae, Pseudomonas aeruginosa and Staphylococcus spp., which are commonly used as biofilm model organisms and therefore contribute to our general understanding of bacterial biofilm (patho-)physiology. Finally, therapeutical intervention strategies targeting biofilms will be discussed. |
format | Online Article Text |
id | pubmed-7841849 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Shared Science Publishers OG |
record_format | MEDLINE/PubMed |
spelling | pubmed-78418492021-02-05 Biofilms by bacterial human pathogens: Clinical relevance - development, composition and regulation - therapeutical strategies Schulze, Adina Mitterer, Fabian Pombo, Joao P. Schild, Stefan Microb Cell Review Notably, bacterial biofilm formation is increasingly recognized as a passive virulence factor facilitating many infectious disease processes. In this review we will focus on bacterial biofilms formed by human pathogens and highlight their relevance for diverse diseases. Along biofilm composition and regulation emphasis is laid on the intensively studied biofilms of Vibrio cholerae, Pseudomonas aeruginosa and Staphylococcus spp., which are commonly used as biofilm model organisms and therefore contribute to our general understanding of bacterial biofilm (patho-)physiology. Finally, therapeutical intervention strategies targeting biofilms will be discussed. Shared Science Publishers OG 2021-02-01 /pmc/articles/PMC7841849/ /pubmed/33553418 http://dx.doi.org/10.15698/mic2021.02.741 Text en Copyright: © 2021 Schulze et al. https://creativecommons.org/licenses/by/4.0/ This is an open-access article released under the terms of the Creative Commons Attribution (CC BY) license, which allows the unrestricted use, distribution, and reproduction in any medium, provided the original author and source are acknowledged. |
spellingShingle | Review Schulze, Adina Mitterer, Fabian Pombo, Joao P. Schild, Stefan Biofilms by bacterial human pathogens: Clinical relevance - development, composition and regulation - therapeutical strategies |
title | Biofilms by bacterial human pathogens: Clinical relevance - development, composition and regulation - therapeutical strategies |
title_full | Biofilms by bacterial human pathogens: Clinical relevance - development, composition and regulation - therapeutical strategies |
title_fullStr | Biofilms by bacterial human pathogens: Clinical relevance - development, composition and regulation - therapeutical strategies |
title_full_unstemmed | Biofilms by bacterial human pathogens: Clinical relevance - development, composition and regulation - therapeutical strategies |
title_short | Biofilms by bacterial human pathogens: Clinical relevance - development, composition and regulation - therapeutical strategies |
title_sort | biofilms by bacterial human pathogens: clinical relevance - development, composition and regulation - therapeutical strategies |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841849/ https://www.ncbi.nlm.nih.gov/pubmed/33553418 http://dx.doi.org/10.15698/mic2021.02.741 |
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