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Heparin Accelerates the Protein Aggregation via the Downhill Polymerization Mechanism: Multi-Spectroscopic Studies to Delineate the Implications on Proteinopathies
[Image: see text] Heparin is one of the members of the glycosaminoglycan (GAG) family, which has been associated with protein aggregation diseases including Alzheimer’s disease, Parkinson’s disease, and prion diseases. Here, we investigate heparin-induced aggregation of bovine serum albumin (BSA) us...
Autores principales: | Ahanger, Ishfaq Ahmad, Parray, Zahoor Ahmad, Nasreen, Khalida, Ahmad, Faizan, Hassan, Md. Imtaiyaz, Islam, Asimul, Sharma, Anurag |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841943/ https://www.ncbi.nlm.nih.gov/pubmed/33521471 http://dx.doi.org/10.1021/acsomega.0c05638 |
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