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MethCORR infers gene expression from DNA methylation and allows molecular analysis of ten common cancer types using fresh-frozen and formalin-fixed paraffin-embedded tumor samples

BACKGROUND: Transcriptional analysis is widely used to study the molecular biology of cancer and hold great biomarker potential for clinical patient stratification. Yet, accurate transcriptional profiling requires RNA of a high quality, which often cannot be retrieved from formalin-fixed, paraffin-e...

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Detalles Bibliográficos
Autores principales: Mattesen, Trine B., Andersen, Claus L., Bramsen, Jesper B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7842045/
https://www.ncbi.nlm.nih.gov/pubmed/33509261
http://dx.doi.org/10.1186/s13148-021-01000-0

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