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Apolipoprotein E4–driven effects on inflammatory and neurotrophic factors in peripheral extracellular vesicles from cognitively impaired, no dementia participants who converted to Alzheimer's disease

INTRODUCTION: In brain, extracellular vesicles (EVs) play an essential role in the neuron‐glia interface and ensure the crosstalk between the brain and the periphery. Some studies now link the pathway dysfunction of the EVs to apolipoprotein E gene variant (APOE ε4) and the risk of progression to Al...

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Detalles Bibliográficos
Autores principales:	Ben Khedher, Mohamed Raâfet, Haddad, Mohamed, Laurin, Danielle, Ramassamy, Charles
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7842191/ https://www.ncbi.nlm.nih.gov/pubmed/33537405 http://dx.doi.org/10.1002/trc2.12124

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