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Celiac Disease and the Autoimmune Web of Endocrinopathies

Gluten-sensitive enteropathy or Celiac disease (CD) is a disease that has become very prevalent in most parts of the globe especially in the western world. Resulting from a chaotic interplay between the backgrounds of autoimmunity and genetics, this disorder targets primarily the gastrointestinal tr...

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Autores principales: Sange, Ibrahim, Mohamed, Mohamed Wael F, Aung, Su, Mereddy, Nakul, Hamid, Pousette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7842251/
https://www.ncbi.nlm.nih.gov/pubmed/33527061
http://dx.doi.org/10.7759/cureus.12383
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author Sange, Ibrahim
Mohamed, Mohamed Wael F
Aung, Su
Mereddy, Nakul
Hamid, Pousette
author_facet Sange, Ibrahim
Mohamed, Mohamed Wael F
Aung, Su
Mereddy, Nakul
Hamid, Pousette
author_sort Sange, Ibrahim
collection PubMed
description Gluten-sensitive enteropathy or Celiac disease (CD) is a disease that has become very prevalent in most parts of the globe especially in the western world. Resulting from a chaotic interplay between the backgrounds of autoimmunity and genetics, this disorder targets primarily the gastrointestinal tract with ominous extraintestinal counterparts that have a very discrete presentation. Among those counterparts, the one that has been reviewed in this article is the involvement of the endocrine system as concurrence of hormonal disorders with CD possesses numerous challenges that lead to a refractory treatment and a dull prognosis. This review article aims to feature the effect of the CD and endocrine disorders on one another, especially if either of the diseases is asymptomatic, explore the clinical dilemma faced by clinicians in various specialties, and, hence, further pave a path into the importance of rigorous screening and diagnosis.
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spelling pubmed-78422512021-01-31 Celiac Disease and the Autoimmune Web of Endocrinopathies Sange, Ibrahim Mohamed, Mohamed Wael F Aung, Su Mereddy, Nakul Hamid, Pousette Cureus Endocrinology/Diabetes/Metabolism Gluten-sensitive enteropathy or Celiac disease (CD) is a disease that has become very prevalent in most parts of the globe especially in the western world. Resulting from a chaotic interplay between the backgrounds of autoimmunity and genetics, this disorder targets primarily the gastrointestinal tract with ominous extraintestinal counterparts that have a very discrete presentation. Among those counterparts, the one that has been reviewed in this article is the involvement of the endocrine system as concurrence of hormonal disorders with CD possesses numerous challenges that lead to a refractory treatment and a dull prognosis. This review article aims to feature the effect of the CD and endocrine disorders on one another, especially if either of the diseases is asymptomatic, explore the clinical dilemma faced by clinicians in various specialties, and, hence, further pave a path into the importance of rigorous screening and diagnosis. Cureus 2020-12-30 /pmc/articles/PMC7842251/ /pubmed/33527061 http://dx.doi.org/10.7759/cureus.12383 Text en Copyright © 2020, Sange et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Endocrinology/Diabetes/Metabolism
Sange, Ibrahim
Mohamed, Mohamed Wael F
Aung, Su
Mereddy, Nakul
Hamid, Pousette
Celiac Disease and the Autoimmune Web of Endocrinopathies
title Celiac Disease and the Autoimmune Web of Endocrinopathies
title_full Celiac Disease and the Autoimmune Web of Endocrinopathies
title_fullStr Celiac Disease and the Autoimmune Web of Endocrinopathies
title_full_unstemmed Celiac Disease and the Autoimmune Web of Endocrinopathies
title_short Celiac Disease and the Autoimmune Web of Endocrinopathies
title_sort celiac disease and the autoimmune web of endocrinopathies
topic Endocrinology/Diabetes/Metabolism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7842251/
https://www.ncbi.nlm.nih.gov/pubmed/33527061
http://dx.doi.org/10.7759/cureus.12383
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