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Proteasomal degradation of human SERINC4: A potent host anti-HIV-1 factor that is antagonized by nef

The serine incorporator (SERINC) protein family has five paralogous members with 9–11 transmembrane domains. SERINC5 is a potent host restriction factor and antagonized by HIV-1 Nef and two other retroviral accessory proteins via the lysosomal degradation pathway. Here, we investigated human SERINC4...

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Detalles Bibliográficos
Autores principales:	Qiu, Xusheng, Eke, Ifeanyichukwu E., Johnson, Silas F., Ding, Chan, Zheng, Yong-Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7842267/ https://www.ncbi.nlm.nih.gov/pubmed/33521797 http://dx.doi.org/10.1016/j.crviro.2020.100002

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